BACKGROUND Patients with ALS may be exposed to variable degrees of chronic intermittent hypoxia. However, all previous experimental studies on the effects of hypoxia in ALS have only used a sustained hypoxia model and it is possible that chronic intermittent hypoxia exerts effects via a different molecular mechanism from that of sustained hypoxia. No study has yet shown that hypoxia (either chr...

OBJECTIVE The objective of this study was to investigate the effects of chronic and intermittent hypoxia on myocardial morphology. METHODS Rats randomly divided into 3 groups (n = 14 per group) were exposed to room air (Fio(2) = 0.21), chronic hypoxia (Fio(2) = 0.10), and intermittent hypoxia (chronic hypoxia with 1 hour per day of room air) for 2 weeks. Weight, blood gas analysis, hematocrit...

Priapism is a condition of persistent involuntary painful erection of the penis, not leading to orgasm. The term derives from Priapus, a Greek fertility god who is represented as an ugly man with an enormous and erect penis. In many cases a cause can be found but in others the condition is idiopathic. If it persists for more than 12 hours, it may affect the patient's potency at a later date. A ...